SERP1 and SEC61A1

Number of citations of the paper that reports this interaction (PubMedID 10601334)
32

Data Source:
HPRD (in vivo)

		SERP1	SEC61A1
Description		stress associated endoplasmic reticulum protein 1	SEC61 translocon subunit alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding
	Biological Process	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Post-embryonic Development Multicellular Organism Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Response To Interferon-gamma Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		53 interacting genes: ACAD11 ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MFSD14B MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A6 SLC22A1 SLC22A2 SLC35C2 SSMEM1 STX1A STX2 STX4 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	12 interacting genes: ACAD9 BAG6 CALM1 GET3 HSPA5 MLH1 PLXND1 PTEN SEC61G SERP1 SLC13A1 TNF
Entrez ID		27230	29927
HPRD ID		18037	15316
Ensembl ID		ENSG00000120742	ENSG00000058262
Uniprot IDs		Q9Y6X1	B3KME8 B3KNF6 P61619
PDB IDs			6W6L
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?