GFRA3 and COL6A3

		GFRA3	COL6A3
Description		GDNF family receptor alpha 3	collagen type VI alpha 3 chain
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GO Annotations	Cellular Component	Cytosol Plasma Membrane External Side Of Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Receptor Complex	Extracellular Region Collagen Type VI Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Signaling Receptor Binding Protein Binding Axon Guidance Receptor Activity Glial Cell-derived Neurotrophic Factor Receptor Activity Signaling Receptor Activity	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Neuron Migration Signal Transduction Nervous System Development Axon Guidance Peripheral Nervous System Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Sympathetic Nervous System Development	Cell Adhesion Muscle Organ Development Negative Regulation Of Endopeptidase Activity
Pathways		RAF/MAP kinase cascade RET signaling	Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) QT interval ( 24952745) Schizophrenia ( 25056061)	Abstraction and mental flexibility ( 31596458) Aging (time to event) ( 21782286) Chronic kidney disease ( 30226566) Coronary artery disease ( 29212778 30402224 33020668) Cortex volume ( 31530798) HDL cholesterol ( 26160806) Heel bone mineral density ( 30598549) Height ( 33713608) Hypertension ( 30226566) Intraocular pressure ( 29617998 29235454) Ischemic stroke ( 29930801) LDL cholesterol ( 26160806) Lung cancer ( 28604730) Myocardial infarction ( 30226566) Pulse pressure ( 27841878)
Interacting Genes		2 interacting genes: ARTN COL6A3	12 interacting genes: ALPG CDT1 DYSF GBX2 GFRA3 KCNJ13 MMP2 NGFR PPT1 SEPTIN2 SUDS3 TRIT1
Entrez ID		2676	1293
HPRD ID		10420	00371
Ensembl ID		ENSG00000146013	ENSG00000163359
Uniprot IDs		O60609	B7ZW00 D9ZGF2 P12111 Q63HQ4 Q8N4Z1
PDB IDs		2GH0 6Q2S	1KNT 1KTH 1KUN 2KNT 6SNK
Enriched GO Terms of Interacting Partners?
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