GFAP and SH3YL1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		GFAP	SH3YL1
Description		glial fibrillary acidic protein	SH3 and SYLF domain containing 1
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GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Intermediate Filament Cell Body Intermediate Filament Cytoskeleton Astrocyte End-foot Cytoplasmic Side Of Lysosomal Membrane	Ruffle Membrane
	Molecular Function	Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding Kinase Binding Identical Protein Binding	Protein Binding Phosphatase Binding Phosphatidylinositol Binding
	Biological Process	Intracellular Protein Transport Response To Wounding Gene Expression Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Neuron Projection Development Astrocyte Development Extracellular Matrix Organization Neuron Projection Regeneration Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Neurotransmitter Uptake Bergmann Glial Cell Differentiation Long-term Synaptic Potentiation D-aspartate Import Across Plasma Membrane Regulation Of Chaperone-mediated Autophagy	Phosphatidylinositol Biosynthetic Process Regulation Of Ruffle Assembly
Pathways		Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases
GWAS		Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)	Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) Blood urea nitrogen levels ( 31152163) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Body shape index ( 34021172) Estimated glomerular filtration rate ( 31152163) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Large artery stroke ( 28265093) Mitochondrial DNA levels ( 25240745) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		83 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 ENKD1 EPM2AIP1 FAM50B FXR1 FXR2 GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCA2 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TSC1 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774	9 interacting genes: AR ERRFI1 GFAP HELZ KHDRBS1 SH3D19 VIM VPS37B ZBTB7B
Entrez ID		2670	26751
HPRD ID		00675	15336
Ensembl ID		ENSG00000131095	ENSG00000035115
Uniprot IDs		P14136	Q96HL8
PDB IDs		6A9P	2D8H
Enriched GO Terms of Interacting Partners?
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