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KAT2A and TCF3
Number of citations of the paper that reports this interaction (PubMedID
28205554
)
52
Data Source:
BioGRID
(fluorescent resonance energy transfer)
KAT2A
TCF3
Description
lysine acetyltransferase 2A
transcription factor 3
Image
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
SAGA Complex
Chromatin
Extracellular Space
Nucleus
Nucleoplasm
Centrosome
Transcription Factor TFTC Complex
Mitotic Spindle
Chromatin
Euchromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Chromatin Binding
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
Transcription Factor Binding
H3 Histone Acetyltransferase Activity
Protein Phosphatase Binding
Histone Deacetylase Binding
Histone Acetyltransferase Activity (H4-K12 Specific)
Peptide-lysine-N-acetyltransferase Activity
Histone Succinyltransferase Activity
Histone Glutaryltransferase Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Homodimerization Activity
BHLH Transcription Factor Binding
Protein Heterodimerization Activity
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Vitamin D Response Element Binding
E-box Binding
DNA-binding Transcription Factor Binding
Biological Process
In Utero Embryonic Development
Somitogenesis
Positive Regulation Of Cytokine Production
Neural Tube Closure
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Heart Development
Long-term Memory
Cell Population Proliferation
Response To Organic Cyclic Compound
Histone Acetylation
Histone Deubiquitination
Internal Peptidyl-lysine Acetylation
Telencephalon Development
Metencephalon Development
Midbrain Development
Positive Regulation Of Cell Projection Organization
Regulation Of Protein Stability
Response To Nutrient Levels
Positive Regulation Of Histone Acetylation
Multicellular Organism Growth
Histone H3 Acetylation
Histone H4-K12 Acetylation
Histone H3-K14 Acetylation
Regulation Of Regulatory T Cell Differentiation
Positive Regulation Of Gluconeogenesis
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Centriole Replication
Regulation Of Synaptic Plasticity
Intracellular Distribution Of Mitochondria
Regulation Of T Cell Activation
Limb Development
Regulation Of Cartilage Development
Cellular Response To Tumor Necrosis Factor
Alpha-tubulin Acetylation
Histone Succinylation
Peptidyl-lysine Glutarylation
Regulation Of Bone Development
Cellular Response To Nerve Growth Factor Stimulus
Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Cardiac Muscle Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
B Cell Lineage Commitment
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
B Cell Differentiation
Immunoglobulin V(D)J Recombination
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HATs acetylate histones
Notch-HLH transcription pathway
B-WICH complex positively regulates rRNA expression
Ub-specific processing proteases
RNA Polymerase I Transcription Initiation
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Myogenesis
Myogenesis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Coenzyme A
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Inflammatory bowel disease (
26278503
)
Mean reticulocyte volume (
32888494
)
Vitiligo (
27723757
)
vWF and FVIII levels (
30586737
)
Hodgkin's lymphoma (
29196614
24920014
)
Monocyte count (
32888494
)
Objective response to lithium treatment (
26503763
)
Triglyceride levels (
34074324
)
Interacting Genes
60 interacting genes:
AKT1
ATXN7
BATF2
BECN1
CCND2
CCNE1
CDK2
CDK6
CDKN2B
CEBPB
COMMD1
CREBBP
CRX
CTNNB1
CUL2
DTL
EID1
EP300
FZR1
GATA2
GRM1
H1-5
H2AC20
H2BC21
H3-4
H3C14
H4-16
H4C14
HSD11B2
IRF1
IRF2
IRF7
KDELR2
LATS2
MAP2K3
MAPK14
MYB
MYC
NF2
NOTCH1
PBX1
PPARG
PRKDC
PYGO2
RASSF1
RBPJ
RELA
SIRT2
STK11
TACC1
TACC2
TACC3
TADA2A
TCF3
TP53
TRRAP
TSC1
TTYH2
UBE2I
XRCC6
68 interacting genes:
AEBP1
ASCL3
AURKA
BHLHA15
BHLHE40
CALM1
CALM3
CBFA2T3
CREBBP
CTNNB1
DACH1
DAXX
ELK3
EP300
FERD3L
GLIS1
HAND1
HAND2
HOXA1
ID1
ID2
ID3
KAT2A
KAT2B
LMX1A
LMX1B
LYL1
MAPK1
MAPK3
MAPKAPK2
MAPKAPK3
MDFI
MEN1
MSC
MYF5
MYF6
MYOD1
MYOG
NEDD9
NEUROD1
NHLH1
NSD3
PARP1
PDX1
PSMD4
PSMD9
RALGAPA1
RPL37
RUNX1T1
SCX
SKP2
SRF
SUPT3H
TADA2A
TAL1
TAL2
TCAF1
TCF12
TCF21
TCF4
TFPT
TLE1
TNFSF14
TRRAP
TWIST1
TWIST2
UBE2I
USF1
Entrez ID
2648
6929
HPRD ID
03807
00918
Ensembl ID
ENSG00000108773
ENSG00000071564
Uniprot IDs
Q92830
A0A0A0MRB7
P15923
X6REB3
PDB IDs
1F68
1Z4R
3D7C
5H84
5H86
5MLJ
5TRL
5TRM
6J3P
1HLH
2MH0
2YPA
2YPB
3U5V
6MGN
Enriched GO Terms of Interacting Partners
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