ERAL1 and MIR138-1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		ERAL1	MIR138-1
Description		Era like 12S mitochondrial rRNA chaperone 1	microRNA 138-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol	Nucleus Cytoplasm
	Molecular Function	RNA Binding Protein Binding GTP Binding RRNA Binding Ribosomal Small Subunit Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Ribosomal Small Subunit Assembly	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Osteoblast Proliferation Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Phosphatidylinositol 3-kinase Activity Plasma Membrane Raft Assembly Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Response To Cytokine Stimulus Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Estimated glomerular filtration rate reduction (30%) ( 30955190) Glycated hemoglobin levels ( 34059833 28898252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 28017375) Mean corpuscular volume ( 29403010) Pulse pressure ( 30224653) Red cell distribution width ( 32888494)	Schizophrenia ( 30285260)
Interacting Genes		47 interacting genes: CEP44 ECT2 MIR1-1 MIR106A MIR106B MIR107 MIR122 MIR138-1 MIR141 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR29B2 MIR34B MIR451A MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7I SSX2IP TMEM97	67 interacting genes: ADARB1 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LRPPRC MARS1 MATR3 NONO NUDT16L1 NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3
Entrez ID		26284	406929
HPRD ID		08466
Ensembl ID		ENSG00000132591	ENSG00000207954
Uniprot IDs		O75616
PDB IDs
Enriched GO Terms of Interacting Partners?
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