AMD1 and THAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AMD1	THAP4
Description		adenosylmethionine decarboxylase 1	THAP domain containing 4
Image
GO Annotations	Cellular Component	Cytosol	Cellular_component
	Molecular Function	Adenosylmethionine Decarboxylase Activity Protein Binding Putrescine Binding Identical Protein Binding	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process	S-adenosylmethioninamine Biosynthetic Process Polyamine Metabolic Process Spermine Biosynthetic Process Spermidine Biosynthetic Process	Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways		Metabolism of polyamines
Drugs		Ademetionine Putrescine 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine
Diseases
GWAS		Blood metabolite levels ( 26401656)	Brain structure ( 20171287) Hip circumference adjusted for BMI ( 34021172) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		2 interacting genes: HSPB1 THAP4	42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		262	51078
HPRD ID		01622	11630
Ensembl ID		ENSG00000123505	ENSG00000176946
Uniprot IDs		A0A088AWN0 B4DZ60 P17707 Q5VXN5 Q6N0B2	Q8WY91
PDB IDs		1I72 1I79 1I7B 1I7C 1I7M 1JEN 1JL0 1MSV 3DZ2 3DZ3 3DZ4 3DZ5 3DZ6 3DZ7 3EP3 3EP4 3EP5 3EP6 3EP7 3EP8 3EP9 3EPA 3EPB 3H0V 3H0W	3IA8
Enriched GO Terms of Interacting Partners?
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