GAMT and RAB24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GAMT	RAB24
Description		guanidinoacetate N-methyltransferase	RAB24, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Endosome Autophagosome Cytosol Plasma Membrane Endomembrane System Endocytic Vesicle Secretory Granule Membrane
	Molecular Function	Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Guanidinoacetate N-methyltransferase Activity	GTPase Activity Protein Binding GTP Binding
	Biological Process	Creatine Metabolic Process Creatine Biosynthetic Process Muscle Contraction Spermatogenesis Animal Organ Morphogenesis Methylation Regulation Of Multicellular Organism Growth	Intracellular Protein Transport Autophagy
Pathways		Creatine metabolism Transcriptional Regulation by MECP2	Neutrophil degranulation RAB geranylgeranylation
Drugs		Creatine Guanidine S-adenosyl-L-homocysteine Glycocyamine Phosphocreatine
Diseases
GWAS			Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Narrowest width of the femoral neck ( 30888730) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: CSNK2B FOS GPX4 POT1 RAB24 TERF1 TERF2IP TRIM39	3 interacting genes: GAMT MTDH RBSN
Entrez ID		2593	53917
HPRD ID		03142	06697
Ensembl ID		ENSG00000130005	ENSG00000169228
Uniprot IDs		Q14353 V9HWB2	Q969Q5
PDB IDs		3ORH
Enriched GO Terms of Interacting Partners?
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