NGEF and MRPL44

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		NGEF	MRPL44
Description		neuronal guanine nucleotide exchange factor	mitochondrial ribosomal protein L44
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Growth Cone	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Plasma Membrane Nuclear Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	RNA Binding Structural Constituent Of Ribosome Ribonuclease III Activity Protein Binding
	Biological Process	Nervous System Development Cell Differentiation Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Dendritic Spine Morphogenesis Activation Of GTPase Activity	RRNA Catabolic Process Mitochondrial Translational Elongation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		NRAGE signals death through JNK EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse G alpha (12/13) signalling events RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Contrast sensitivity ( 24152035) Heel bone mineral density ( 30598549 28869591) Parkinson's disease ( 32201043) Pursuit maintenance gain ( 29064472) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Sudden cardiac arrest ( 30169657) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		18 interacting genes: ATP5F1C C7orf25 C8orf33 EPHA4 FAM118B HCK MRPL44 NUDT21 RHOA SEPTIN2 SH2D1A SMO TAF1D TRIM55 TRIM63 TTK USP25 YIPF3	15 interacting genes: ABI2 CEP70 DGKE IMMT ITFG1 NGEF PI4KA PLPP2 PTN SEMA5B SETDB1 SHC1 USP22 VIM ZNF235
Entrez ID		25791	65080
HPRD ID		10442	14763
Ensembl ID		ENSG00000066248	ENSG00000135900
Uniprot IDs		B4DDI2 Q8N5V2	A1MA90 Q9H9J2
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?