PTF1A and PALS2

		PTF1A	PALS2
Description		pancreas associated transcription factor 1a	protein associated with LIN7 2, MAGUK p55 family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development	Protein-containing Complex Assembly
Pathways		Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases
GWAS		Type 2 diabetes ( 32499647)
Interacting Genes		12 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B PALS2 RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10	37 interacting genes: AATF ABCA1 ADGRA1 ARF5 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MKRN2 MT2P1 MTREX NDN NFKB1 OGT OSBPL3 PARN PTF1A RPS20 SMARCA4 SNX9 TACR3 THOP1
Entrez ID		256297	51678
HPRD ID		09526	09509
Ensembl ID		ENSG00000168267	ENSG00000105926
Uniprot IDs		Q7RTS3	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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