SYCE2 and TRIML2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SYCE2	TRIML2
Description		synaptonemal complex central element protein 2	tripartite motif family like 2
Image			No pdb structure
GO Annotations	Cellular Component	Central Element Nucleoplasm Chromosome	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Synaptonemal Complex Assembly Cell Division	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494)	Polycystic ovary syndrome ( 25574032)
Interacting Genes		13 interacting genes: CCDC196 CDC37 GAD2 HOMER1 IFT20 KIFC3 MED11 MED4 NAP1L5 TEX12 TRIM69 TRIML2 TSNAX	48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3
Entrez ID		256126	205860
HPRD ID		19522	08696
Ensembl ID		ENSG00000161860	ENSG00000179046
Uniprot IDs		Q6PIF2	B7ZLC3 Q8N7C3
PDB IDs		6R17
Enriched GO Terms of Interacting Partners?
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