KCTD13 and VTA1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCTD13	VTA1
Description		potassium channel tetramerization domain containing 13	vesicle trafficking 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein Domain Specific Binding Small GTPase Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation	Protein Transport Macroautophagy Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly
Pathways		RND3 GTPase cycle RND2 GTPase cycle	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 28991256 25056061 29483656 30285260) Urinary sodium excretion ( 31409800)	Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578) Retinal vascular caliber ( 21060863) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes		22 interacting genes: ADRB2 ARMC7 CDC37 CRK CUL3 EXOSC5 FXR1 GORASP2 KAT7 KCTD10 LNX1 NTAQ1 NUDT18 PCNA POLD2 POLR1C PPARG PSMA1 RHOA TNFAIP1 VTA1 ZMYND19	22 interacting genes: APP BEX3 CBS CCNC CDK4 CHMP1A CHMP1B CHMP5 DPPA2 ERBB3 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA TEAD4 ZBTB16 ZNRD2
Entrez ID		253980	51534
HPRD ID		12339	09855
Ensembl ID		ENSG00000174943	ENSG00000009844
Uniprot IDs		A0A3B3IS45 Q8WZ19	A0A087WY55 Q9NP79
PDB IDs		4UIJ	2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E
Enriched GO Terms of Interacting Partners?
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