FUT1 and VPS11

		FUT1	VPS11
Description		fucosyltransferase 1 (H blood group)	VPS11 core subunit of CORVET and HOPS complexes
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Plasma Membrane Membrane Golgi Cisterna Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane
	Molecular Function	Galactoside 2-alpha-L-fucosyltransferase Activity Fucosyltransferase Activity Alpha-(1,2)-fucosyltransferase Activity	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cell-matrix Adhesion Carbohydrate Metabolic Process Protein Glycosylation Oligosaccharide Biosynthetic Process Positive Regulation Of Endothelial Cell Migration Olfactory Bulb Development Regulation Of Cell Adhesion Fucosylation L-fucose Catabolic Process Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Organelle Fusion Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		ABO blood group biosynthesis
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Bipolar disorder ( 21926972) Cooked vegetable consumption ( 32066663) Dietary macronutrient intake ( 23372041) Elevated serum carcinoembryonic antigen levels ( 24941225) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Intake of total sugars ( 31005972) Meat-related diet ( 32066663) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Retinal vascular caliber ( 21060863) Serum alkaline phosphatase levels ( 33339817) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Adult body size ( 32376654) Body mass index ( 29273807) Coronary artery disease ( 29212778 33020668) HDL cholesterol levels ( 32203549) Plateletcrit ( 32888494)
Interacting Genes		1 interacting genes: VPS11	38 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS39 VPS45 WNT1
Entrez ID		2523	55823
HPRD ID		07186	12258
Ensembl ID		ENSG00000174951	ENSG00000160695
Uniprot IDs		P19526 Q6IZA2	A0A087WXL6 B7Z879 Q9H270
PDB IDs
Enriched GO Terms of Interacting Partners?
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