PANX1 and BUD31

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		PANX1	BUD31
Description		pannexin 1	BUD31 homolog
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Membrane Integral Component Of Membrane Bleb Protein-containing Complex	Chromatin Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Protease Binding Signaling Receptor Binding Structural Molecule Activity Calcium Channel Activity Protein Binding Wide Pore Channel Activity Leak Channel Activity Transmembrane Transporter Binding Actin Filament Binding Gap Junction Hemi-channel Activity Scaffold Protein Binding	Protein Binding Nuclear Receptor Binding Nuclear Receptor Coactivator Activity
	Biological Process	Response To Ischemia Cation Transport Calcium Ion Transport Cell-cell Signaling Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Interleukin-1 Beta Production Response To ATP Oogenesis Calcium Ion Transmembrane Transport	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Androgen Receptor Activity
Pathways		Electric Transmission Across Gap Junctions The NLRP3 inflammasome	mRNA Splicing - Major Pathway
Drugs		Probenecid
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874 33339817) Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 33547301 34315874 29403010 33339817) Autoimmune thyroid disease ( 32581359) Liver enzyme levels (alanine transaminase) ( 33972514) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Squamous cell lung carcinoma ( 28604730)	Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		17 interacting genes: APOA2 APOL2 AQP2 BCL2L2 BUD31 CFHR5 CLCA4 FAXDC2 FDFT1 GNAS KEAP1 P2RX7 SLC38A7 TMEM229B TNF VAMP5 WFDC2	23 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 TMEM94 TSPAN7
Entrez ID		24145	8896
HPRD ID		10526	10351
Ensembl ID		ENSG00000110218	ENSG00000106245
Uniprot IDs		A0A024R397 Q96RD7	P41223
PDB IDs		6LTN 6LTO 6M02 6M66 6M67 6M68 6V6D 6WBF 6WBG 6WBI 6WBK 6WBL 6WBM 6WBN	4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7AAV 7ABF 7ABG 7ABI
Enriched GO Terms of Interacting Partners?
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