IFIT5 and IFIT1

Number of citations of the paper that reports this interaction (PubMedID 21642987)
222

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IFIT5	IFIT1
Description		interferon induced protein with tetratricopeptide repeats 5	interferon induced protein with tetratricopeptide repeats 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell	Cytoplasm Cytosol Host Cell
	Molecular Function	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding	RNA Binding Protein Binding
	Biological Process	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus	Response To Virus Intracellular Transport Of Viral Protein In Host Cell Negative Regulation Of Protein Binding Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of Defense Response To Virus Negative Regulation Of Helicase Activity Defense Response To Virus Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA Antiviral Innate Immune Response
Pathways		Interferon alpha/beta signaling	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: A2M APOE CDC37 CHUK ECSIT IFIT1 IFIT3 IKBKG LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2	4 interacting genes: EIF3E IFIT2 IFIT3 IFIT5
Entrez ID		24138	3434
HPRD ID		17130	00983
Ensembl ID		ENSG00000152778	ENSG00000185745
Uniprot IDs		Q13325	P09914
PDB IDs		3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U	4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K
Enriched GO Terms of Interacting Partners?
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