TMEFF2 and RIC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEFF2	RIC3
Description		transmembrane protein with EGF like and two follistatin like domains 2	RIC3 acetylcholine receptor chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Plasma Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse
	Molecular Function	Molecular_function Protein Binding	Acetylcholine Receptor Binding Protein Folding Chaperone
	Biological Process	Animal Organ Morphogenesis Tissue Development Cell Migration Negative Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Wound Healing, Spreading Of Cells Negative Regulation Of Integrin Biosynthetic Process Negative Regulation Of Stress Fiber Assembly	Protein Folding Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission, Cholinergic Protein Localization To Cell Surface Cellular Protein-containing Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways
Drugs			Theophylline
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Adverse response to drug ( 30420678) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Diabetes (incident) ( 17903298) Schizophrenia ( 33169155) Sudden cardiac arrest ( 21658281)	Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Malaria ( 31844061)
Interacting Genes		12 interacting genes: DNAH7 DRD2 HSF2BP HTR4 NBPF19 NOTCH2NLA RIC3 STAT4 TMEM237 TRHR UBIAD1 ZDHHC15	16 interacting genes: BCL2L1 CACNA1C CLN6 FA2H FATE1 GOSR2 NINJ2 PRB1 STX12 STX7 TMBIM1 TMEFF2 TMEM11 TMEM86A TRAF3IP3 YIF1A
Entrez ID		23671	79608
HPRD ID		05760	17974
Ensembl ID		ENSG00000144339	ENSG00000166405
Uniprot IDs		Q9UIK5	A0A0S2Z607 A0A0S2Z6D3 B7Z3Z0 D3DQU6 Q7Z5B4
PDB IDs		2FMW
Enriched GO Terms of Interacting Partners?
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