TNPO3 and ECI2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNPO3	ECI2
Description		transportin 3	enoyl-CoA delta isomerase 2
Image
GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Fatty-acyl-CoA Binding Dodecenoyl-CoA Delta-isomerase Activity Protein Binding
	Biological Process	Protein Import Into Nucleus	Fatty Acid Beta-oxidation
Pathways
Drugs			Myristic acid
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 32771030 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)	Blood metabolite levels ( 24816252) Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B	4 interacting genes: APP KDM1A PEX5 TNPO3
Entrez ID		23534	10455
HPRD ID		18209	16269
Ensembl ID		ENSG00000064419	ENSG00000198721
Uniprot IDs		A0A024R794 B3KMX1 Q9Y5L0	A0A0C4DGA2 O75521
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9	2CQU 2F6Q 4U18 4U19 4U1A
Enriched GO Terms of Interacting Partners?
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