MMD and MS4A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MMD	MS4A1
Description		monocyte to macrophage differentiation associated	membrane spanning 4-domains A1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Golgi Apparatus Integral Component Of Plasma Membrane Membrane Late Endosome Membrane	Extracellular Space Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Plasma Membrane Raft Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding Signaling Receptor Activity	Epidermal Growth Factor Receptor Binding Protein Binding Immunoglobulin Binding MHC Class II Protein Complex Binding Identical Protein Binding
	Biological Process	Protein Phosphorylation Cytolysis Regulation Of Protein Localization Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity	Store-operated Calcium Entry Humoral Immune Response Response To Bacterium B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway Protein Tetramerization Calcium Ion Import Into Cytosol
Pathways
Drugs			Rituximab Ibritumomab tiuxetan Tositumomab Ofatumumab Obinutuzumab Technetium Tc-99m nofetumomab merpentan Ocrelizumab
Diseases
GWAS		Heel bone mineral density ( 30598549) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)	Recurrent major depressive disorder ( 29317602)
Interacting Genes		19 interacting genes: AGTRAP ARL13B ATP13A1 C4orf3 CYP4F2 EMC6 FAM209A GAST GPR152 GPX8 MS4A1 OCIAD1 PLEKHO1 SELENOK SFXN1 TMEM203 TMEM42 TMEM60 YIPF6	41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MFSD14B MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35C2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2
Entrez ID		23531	931
HPRD ID		06835	00204
Ensembl ID		ENSG00000108960	ENSG00000156738
Uniprot IDs		A0A3B3ITQ3 Q15546	A0A024R507 P11836
PDB IDs			1S8B 2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A
Enriched GO Terms of Interacting Partners?
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