ZFYVE26 and PRDM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZFYVE26	PRDM6
Description		zinc finger FYVE-type containing 26	PR/SET domain 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Centrosome Midbody	Nucleus
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Protein Binding Histone Methyltransferase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination Regulation Of Cytokinesis	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Histone Methylation Neurogenesis Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)	Body mass index ( 28892062) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 27618447) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Male-pattern baldness ( 28196072) Mammographic density (dense area) ( 25342443) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Percent mammographic density ( 25342443) Pulse pressure ( 27841878 27618447) QRS duration ( 25035420) Systolic blood pressure ( 26390057 27841878 27618447 30578418)
Interacting Genes		35 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20	70 interacting genes: ABI2 AGXT AHCYL1 ANKS1A AQP1 ARID5A ATPAF2 ATXN7L2 BAG3 BANF2 BANP C1orf109 CBFA2T2 CBX8 CCDC120 CCDC57 CCHCR1 CCNL1 CEP57L1 COX5B CSTF2 ELOA ENKD1 EXOSC5 FAM214B FAM90A1 FHL2 FOXD4L1 FRS3 FTO GADD45GIP1 GEM GPANK1 GRXCR1 HOXC8 IL16 IQUB KANK2 KAT5 KCTD9 KIFC3 LMO1 LMO2 LONRF1 MYOZ3 NCK2 NEK6 NFKBID PATZ1 PIH1D2 PRKAA2 PTK6 QARS1 RAD51D ROPN1 RUNX1T1 SAMD4A STK16 TCAF1 TEKT4 TLE5 TRIM14 TRMT12 TSGA10 TSGA10IP TSSK3 TTC23 UBASH3A USP54 ZFYVE26
Entrez ID		23503	93166
HPRD ID		15734	19698
Ensembl ID		ENSG00000072121	ENSG00000061455
Uniprot IDs		A0A7I2YQU3 Q68DK2	Q9NQX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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