HARS2 and MIRLET7F1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		HARS2	MIRLET7F1
Description		histidyl-tRNA synthetase 2, mitochondrial	microRNA let-7f-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Extracellular Space Extracellular Exosome
	Molecular Function	RNA Binding Histidine-tRNA Ligase Activity Protein Binding ATP Binding Identical Protein Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Histidyl-tRNA Aminoacylation	Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of TOR Signaling Negative Regulation Of Interleukin-17 Production Gene Silencing By MiRNA Negative Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Amyloid-beta
Pathways		Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Schizophrenia ( 29483656) Serum immune biomarker levels ( 32066700)
Interacting Genes		22 interacting genes: AGTRAP BST2 MIR106B MIR128-2 MIR141 MIR145 MIR16-2 MIR17 MIR18B MIR199A1 MIR19B1 MIR19B2 MIR29A MIR29B1 MIR34A MIR34B MIR9-1 MIR92A2 MIR93 MIRLET7F1 MIRLET7I OGT	93 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM47 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		23438	406888
HPRD ID		02871
Ensembl ID		ENSG00000112855	ENSG00000199072
Uniprot IDs		A0A2R8Y6I1 B4DDN8 P49590
PDB IDs
Enriched GO Terms of Interacting Partners?
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