RHOQ and CDC42EP1

Number of citations of the paper that reports this interaction (PubMedID 10490598)
45

Data Source:
HPRD (two hybrid, in vitro)

		RHOQ	CDC42EP1
Description		ras homolog family member Q	CDC42 effector protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Actin Filament Plasma Membrane Golgi-associated Vesicle Membrane Membrane Raft Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Endomembrane System
	Molecular Function	GTPase Activity Protein Binding Profilin Binding GTP Binding GBD Domain Binding	Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Endocytosis Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cell-cell Adhesion
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle	CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		23 interacting genes: BANP CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DHFR DOCK8 EXOC7 GOPC MORN4 NTAQ1 PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL ZNF417	15 interacting genes: AP1B1 ARMC7 CDC42 DEF6 FHL3 KRTAP4-12 MAPKAP1 MDFI OGT PLSCR1 PRKAA2 RBPMS RHOJ RHOQ SAT1
Entrez ID		23433	11135
HPRD ID		05791	07303
Ensembl ID		ENSG00000119729	ENSG00000128283
Uniprot IDs		D6W5A7 P17081 V9HWD0	Q00587
PDB IDs		2ATX
Enriched GO Terms of Interacting Partners?
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