DOCK9 and MYOT

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		DOCK9	MYOT
Description		dedicator of cytokinesis 9	myotilin
Image
GO Annotations	Cellular Component	Cytosol Endomembrane System Membrane	Plasma Membrane Actin Cytoskeleton Z Disc Axon Sarcolemma Neuronal Cell Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Cadherin Binding	Actin Binding Protein Binding Axon Guidance Receptor Activity Structural Constituent Of Muscle Alpha-actinin Binding
	Biological Process	Small GTPase Mediated Signal Transduction Biological_process Positive Regulation Of GTPase Activity	Muscle Contraction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Synapse Organization
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Blood urea nitrogen levels ( 31152163 29403010) Corneal astigmatism ( 30306274) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Lung function (FEV1/FVC) ( 30804560) Myocardial infarction ( 33532862) Nonsyndromic cleft palate ( 31609978) Platelet distribution width ( 32888494) QRS interval (sulfonylurea treatment interaction) ( 27958378) Refractive error ( 32231278) White blood cell count ( 32888494)	Atrial fibrillation ( 30061737) Heart rate ( 23583979) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		11 interacting genes: ATG12 CDC42 CLK1 FHL1 LNX1 MYOT NEDD9 NUCKS1 PPP2R5E SNAPIN TAF1	17 interacting genes: ACTN1 ACTN2 ACTN3 APP AXIN1 DOCK9 FLNA FLNC GPRASP2 LRP12 NME7 PDLIM3 PFDN5 ST7 TFG TRIM55 TRIM63
Entrez ID		23348	9499
HPRD ID		09542	04981
Ensembl ID		ENSG00000088387	ENSG00000120729
Uniprot IDs		A0A0A0MT38 A6H8Z6 B3KXE2 B7Z2G6 B9EG73 Q9BZ29	A0A0C4DFM5 B4DT68 Q9UBF9
PDB IDs		1WG7 2WM9 2WMN 2WMO	2KDG 2KKQ
Enriched GO Terms of Interacting Partners?
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