VPS39 and VPS11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VPS39	VPS11
Description		VPS39 subunit of HOPS complex	VPS11 core subunit of CORVET and HOPS complexes
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Membrane AP-3 Adaptor Complex HOPS Complex Late Endosome Membrane Lysosomal HOPS Complex	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Autophagy Endosome To Lysosome Transport Endocytic Recycling Endosomal Vesicle Fusion Autophagosome-lysosome Fusion Late Endosome To Lysosome Transport	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Organelle Fusion Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 29273807) Coronary artery disease ( 29212778 33020668) HDL cholesterol levels ( 32203549) Plateletcrit ( 32888494)
Interacting Genes		10 interacting genes: HOOK1 NUSAP1 OIP5 RAB7A RILP RTF1 SNW1 STAT3 TFIP11 VPS11	38 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS39 VPS45 WNT1
Entrez ID		23339	55823
HPRD ID		10300	12258
Ensembl ID		ENSG00000166887	ENSG00000160695
Uniprot IDs		A0A024R9L9 Q96JC1	A0A087WXL6 B7Z879 Q9H270
PDB IDs		6ZE9
Enriched GO Terms of Interacting Partners?
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