SZT2 and CRX

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SZT2	CRX
Description		SZT2 subunit of KICSTOR complex	cone-rod homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Peroxisome KICSTOR Complex	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Receptor Binding Leucine Zipper Domain Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Central Nervous System Development Post-embryonic Development Corpus Callosum Morphogenesis Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Pigmentation Protein Localization To Lysosome Regulation Of Superoxide Dismutase Activity Negative Regulation Of TORC1 Signaling	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hemoglobin levels ( 32327693) Monocyte count ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30224653 30578418)	Serum metabolite levels ( 33031748)
Interacting Genes		5 interacting genes: CRX REL TCF4 TEPSIN ZNF655	112 interacting genes: AASDHPPT ABI2 ACBD4 ARIH2 ATG12 ATM ATP6V0D2 ATXN1 ATXN7 BANF1 BANF2 BANP BOD1L2 C19orf25 C1orf109 C1orf50 C1orf56 C9orf72 CA8 CCNC CDKN2C CFAP206 CREBBP CSNK1G2-AS1 CTNNA3 DELE1 EIF5A EP300 FAAP20 FOXH1 GCM2 GLIS2 GUCD1 GYS1 HGS HNF1B IGFN1 IPO13 IRX6 KANK2 KAT2A KLHL32 LARP4 LGALS3 LIMS3 LIMS4 LNX1 LONRF1 M1AP MDFI MLLT6 MYO15B MYOZ1 NEIL2 NFYC NIP7 NPAS2 NR2E3 NRL NTF4 OR6B1 OSGIN1 OSTF1 PDC PICALM PID1 PNMA6A POGZ PPP1R16B PRKAB2 PRKN PRR35 PSMA1 PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS RHOXF2 ROR2 SAE1 SDCBP SEC14L4 SFI1 SMAD3 SMAP1 SMAP2 SMUG1 SOX10 SOX14 SOX3 SOX5 SPG21 STK16 SUFU SUOX SZT2 TBX6 TCF7L2 TEX33 TFG TLE5 TLX3 TNS2 UBXN2B UBXN7 VPS37C ZC3H10 ZIC1 ZNF483 ZNF688
Entrez ID		23334	1406
HPRD ID		11085	03748
Ensembl ID		ENSG00000198198	ENSG00000105392
Uniprot IDs		Q5T011	O43186
PDB IDs
Enriched GO Terms of Interacting Partners?
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