FMO3 and SERPINC1

		FMO3	SERPINC1
Description		flavin containing dimethylaniline monoxygenase 3	serpin family C member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Trimethylamine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding
	Biological Process		Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Regulation Of Blood Coagulation, Intrinsic Pathway
Pathways		FMO oxidises nucleophiles Defective FMO3 causes TMAU	Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human
Diseases
GWAS		Blood metabolite levels ( 24816252) Lentiform nucleus volume ( 22903471) Serum metabolite levels ( 33031748)	Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)
Interacting Genes		5 interacting genes: CLEC10A CREB3 SACM1L SERPINC1 SGSM3	14 interacting genes: ATP1B1 CHML CREG1 F2 FMO3 HSP90AA1 KLK1 KLK2 KLK6 MRPS14 PIGC PLG QSOX1 SDC2
Entrez ID		2328	462
HPRD ID		00633	00122
Ensembl ID		ENSG00000007933	ENSG00000117601
Uniprot IDs		A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5	A0A024R944 P01008
PDB IDs			1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1
Enriched GO Terms of Interacting Partners?
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