RPRD2 and VPS45

		RPRD2	VPS45
Description		regulation of nuclear pre-mRNA domain containing 2	vacuolar protein sorting 45 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase II, Holoenzyme	Golgi Membrane Cellular_component Golgi Apparatus Synaptic Vesicle Endosome Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Complex Binding	Molecular_function Protein Binding
	Biological Process	MRNA 3'-end Processing	Intracellular Protein Transport Vesicle-mediated Transport
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Bitter non-alcoholic beverage consumption ( 31046077) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Broad depression or bipolar disorder ( 30626913) Caffeine consumption from tea ( 33287642) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Neutrophil count ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Hip circumference adjusted for BMI ( 34021172) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)
Interacting Genes		9 interacting genes: CSNK2A1 CTDSP1 MTNR1B PLEKHO1 PPP1CA PPP1CC SPOP UPF1 VPS45	16 interacting genes: BCAR3 C1orf43 CASP8 H2AC18 IGF1R PAX2 PTPN1 RAB13 RB1CC1 RBSN RPRD2 SNTG1 STX16 SV2A VPS11 VPS18
Entrez ID		23248	11311
HPRD ID		11084	10301
Ensembl ID		ENSG00000163125	ENSG00000136631
Uniprot IDs		Q5VT52	A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7
PDB IDs		4FLB
Enriched GO Terms of Interacting Partners?
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