MAPK8IP3 and KLC1

Number of citations of the paper that reports this interaction (PubMedID 11106729)
119

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MAPK8IP3	KLC1
Description		mitogen-activated protein kinase 8 interacting protein 3	kinesin light chain 1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm Axon Cytoplasm	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Signaling Receptor Complex Adaptor Activity	Cytoskeletal Motor Activity Protein Binding
	Biological Process	Vesicle-mediated Transport Axon Regeneration Negative Regulation Of Apoptotic Process Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Stabilization Axon Development Anterograde Axonal Protein Transport	Stress Granule Disassembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Signaling by ALK fusions and activated point mutants Kinesins
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		27 interacting genes: ARL4D CASP3 FXR1 KLC1 KLC2 LDLRAP1 MAP2K1 MAP2K4 MAP2K7 MAP3K11 MAP3K5 MAPK10 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 PTK2 RAD51 RAD51D RAF1 RIC8A SRC SULT4A1 TLR2 TLR4 TLR9 ZNF575	33 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CDC42BPB CLSTN1 ERBB2 F2RL1 GPR132 HSPB1 JAG2 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 POLR1E PTGER4 SNCA SPAG9 TACC3 TSC1 YWHAB
Entrez ID		23162	3831
HPRD ID		12014	02489
Ensembl ID		ENSG00000138834	ENSG00000126214
Uniprot IDs		A0A087WYG2 B7ZMF3 E9PFH7 Q9UPT6	Q07866 Q7RTQ2
PDB IDs		4PXJ	3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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