SMC5 and EID3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SMC5	EID3
Description		structural maintenance of chromosomes 5	EP300 interacting inhibitor of differentiation 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Sex Chromosome Nucleus Nucleoplasm Cytoplasm PML Body Nuclear Speck Cell Junction Smc5-Smc6 Complex Interchromatin Granule Site Of Double-strand Break	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Smc5-Smc6 Complex
	Molecular Function	Protein Binding ATP Binding	Protein Binding
	Biological Process	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Nonhomologous End Joining Cellular Response To DNA Damage Stimulus Sister Chromatid Cohesion Internal Peptidyl-lysine Acetylation Stem Cell Population Maintenance Chromosome Condensation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Mitotic Cell Cycle Phase Transition Cell Division Positive Regulation Of Chromosome Segregation Protein Localization To Chromosome, Centromeric Region Cellular Senescence	DNA Repair DNA Recombination
Pathways		SUMOylation of DNA damage response and repair proteins	SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180)	Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
Interacting Genes		6 interacting genes: DISC1 EID3 NSMCE2 SLF2 SMN1 TK1	5 interacting genes: APPBP2 CREBBP FBXO25 SMC5 TRIM31
Entrez ID		23137	493861
HPRD ID		10241	17415
Ensembl ID		ENSG00000198887	ENSG00000255150
Uniprot IDs		Q8IY18	A0A140VJI9 Q8N140
PDB IDs
Enriched GO Terms of Interacting Partners?
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