CUL9 and UBE2G1

Number of citations of the paper that reports this interaction (PubMedID 25028717)
22

Data Source:
BioGRID (pull down)

		CUL9	UBE2G1
Description		cullin 9	ubiquitin conjugating enzyme E2 G1
Image
GO Annotations	Cellular Component	Cytosol Cullin-RING Ubiquitin Ligase Complex	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Transferase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Ubiquitination	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination
Pathways		Neddylation	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adult hearing difficulty ( 31564434) General risk tolerance (MTAG) ( 30643258) Obesity-related traits ( 23251661) Tea consumption ( 31046077) Waist-to-hip ratio adjusted for BMI ( 34021172)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma trimethylamine N-oxide levels ( 28439531) Refractive error ( 32231278) Schizophrenia ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Small cell lung carcinoma ( 28604730)
Interacting Genes		8 interacting genes: CYCS MTDH PLXNB3 TP53 UBE2E2 UBE2G1 UBE2G2 UBE2L3	20 interacting genes: AMFR APP CBL CUL9 DIO2 FBXL2 HUWE1 ITCH MAP3K1 MARCHF6 PRKN RBCK1 RBX1 RC3H1 SMURF1 SYVN1 TRIM63 UBA1 UBE2E1 UBE3A
Entrez ID		23113	7326
HPRD ID		06317	03340
Ensembl ID		ENSG00000112659	ENSG00000132388
Uniprot IDs		Q8IWT3	P62253
PDB IDs		2JUF	2AWF 6D68
Enriched GO Terms of Interacting Partners?
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