FOXD2 and KRTAP21-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FOXD2	KRTAP21-2
Description		forkhead box D2	keratin associated protein 21-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol Intermediate Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Keratinization
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Cortical volume ( 32963231) Estimated glomerular filtration rate ( 31152163) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Male-pattern baldness ( 29146897) Microalbuminuria ( 31511532) Obesity-related traits ( 23251661) Response to anti-depressant treatment in major depressive disorder ( 22041458) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Vaginal microbiome composition (L. iners) ( 32723796)
Interacting Genes		18 interacting genes: ARID5A CADPS CYSRT1 FOXH1 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 NOTO POU2AF1 TEX37 TLE5	30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1
Entrez ID		2306	337978
HPRD ID		03735	11215
Ensembl ID		ENSG00000186564	ENSG00000187026
Uniprot IDs		O60548	Q3LI59
PDB IDs
Enriched GO Terms of Interacting Partners?
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