FOXM1 and UCHL3

Number of citations of the paper that reports this interaction (PubMedID 31598398)
5

Data Source:
BioGRID (enzymatic study)

		FOXM1	UCHL3
Description		forkhead box M1	ubiquitin C-terminal hydrolase L3
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding	Thiol-dependent Deubiquitinase Protein Binding Peptidase Activity NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Regulation Of Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Positive Regulation Of Cell Population Proliferation Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cell Population Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Ras Protein Signal Transduction Regulation Of Cell Cycle Negative Regulation Of Cell Aging Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Double-strand Break Repair	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Catabolic Process Post-translational Protein Modification
Pathways		Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition	UCH proteinases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Neddylation
Drugs
Diseases
GWAS		Height ( 31562340)	Diabetic retinopathy ( 23562823) Metabolite levels ( 23823483)
Interacting Genes		18 interacting genes: BANP CCNE1 CDK1 CDK2 CDK4 CDK6 CHEK2 CREBBP DCAF1 OS9 OTUB1 SIRT1 STAT3 SUMO1 UBE2I UCHL3 USP21 ZBTB3	22 interacting genes: ATM ATXN7L3 CDH1 FOXM1 LONRF1 NEDD8 NSG2 PJA1 PKD2 PLA2G2A POGK RAD51 TRIM27 TRIM54 TRIM55 TRIM63 UBC UBE2S USP15 USP21 USP28 XRCC5
Entrez ID		2305	7347
HPRD ID		03823	04367
Ensembl ID		ENSG00000111206	ENSG00000118939
Uniprot IDs		A0A0D9SFF0 A0A2P9DTZ1 A0A2P9DTZ8 A8K591 Q08050 Q53Y49	A0A087WTB8 A0A140VJZ4 P15374
PDB IDs		3G73	1UCH 1XD3 6ISU 6QML
Enriched GO Terms of Interacting Partners?
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