MAST1 and OGA

Number of citations of the paper that reports this interaction (PubMedID 21163940)
36

Data Source:
BioGRID (two hybrid)

		MAST1	OGA
Description		microtubule associated serine/threonine kinase 1	O-GlcNAcase
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body	Nucleus Cytosol Membrane
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity	Hyalurononglucosaminidase Activity Beta-N-acetylglucosaminidase Activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase Activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase Activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase Activity
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction	N-acetylglucosamine Metabolic Process Protein O-linked Glycosylation Glycoprotein Catabolic Process Protein Deglycosylation Glycoprotein Metabolic Process
Pathways
Drugs		Fostamatinib	Streptozocin
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		41 interacting genes: A2M ACE2 AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 STUB1	10 interacting genes: A2M C6 CDC37 CSNK2B DHX9 GSK3B MAST1 OGT PSEN2 RNF32
Entrez ID		22983	10724
HPRD ID		17469	04949
Ensembl ID		ENSG00000105613	ENSG00000198408
Uniprot IDs		Q9Y2H9	O60502
PDB IDs		2M9X 3PS4	2YDQ 5M7R 5M7S 5M7T 5M7U 5TKE 5UHK 5UHL 5UHO 5UHP 5UN8 5UN9 5VVO 5VVT 5VVU 5VVV 5VVX 6HKI 6PM9
Enriched GO Terms of Interacting Partners?
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