CD93 and MBL2

Number of citations of the paper that reports this interaction (PubMedID 9476117)
26

Data Source:
HPRD (in vitro)

		CD93	MBL2
Description		CD93 molecule	mannose binding lectin 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Secretory Granule Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Extracellular Region Collagen Trimer Extracellular Space Cell Surface Collagen-containing Extracellular Matrix
	Molecular Function	Complement Component C1q Complex Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity	Signaling Receptor Binding Protein Binding Mannose Binding Identical Protein Binding Calcium-dependent Protein Binding
	Biological Process	Phagocytosis Macrophage Activation Cell-cell Adhesion	Complement Activation, Lectin Pathway Acute-phase Response Complement Activation, Classical Pathway Response To Oxidative Stress Opsonization Defense Response To Bacterium Innate Immune Response Negative Regulation Of Viral Process Defense Response To Gram-positive Bacterium
Pathways		Neutrophil degranulation	Lectin pathway of complement activation Initial triggering of complement
Drugs			O3-Sulfonylgalactose Methyl alpha-D-mannoside 4-(Hydrogen sulfate)-beta-D-galactopyranose Methyl beta-L-fucopyranoside N-acetyl-alpha-neuraminic acid alpha-L-methyl-fucose Alpha-Methyl-N-Acetyl-D-Glucosamine
Diseases
GWAS		Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)	Age-related macular degeneration ( 23326517) Blood protein levels ( 30072576 29875488 28240269) Bone properties (heel) ( 24430505) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Bone ultrasound measurement (velocity of sound) ( 28472463) Chin dimples ( 27182965) Emphysema imaging phenotypes ( 26030696) Femoral neck bone mineral density ( 29499414) Fractures ( 30158200 30598549) Heel bone mineral density ( 30598549 28869591) Lumbar spine bone mineral density ( 29499414 22504420) Metabolite levels ( 23823483) Monobrow ( 27182965) Rosacea symptom severity ( 29771307)
Interacting Genes		25 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 ITGB1 KIR2DL2 KNG1 MBL2 MMRN2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2	10 interacting genes: ANK3 CALCR CALR CD93 KRT1 MAD2L1 MASP1 MASP2 PTPRC UBQLN2
Entrez ID		22918	4153
HPRD ID		00396	01107
Ensembl ID		ENSG00000125810	ENSG00000165471
Uniprot IDs		Q9NPY3	P11226
PDB IDs			1HUP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?