EPN2 and WBP1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EPN2	WBP1L
Description		epsin 2	WW domain binding protein 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin Vesicle Coat Clathrin Coat Of Endocytic Vesicle Intracellular Membrane-bounded Organelle	Integral Component Of Membrane
	Molecular Function	Protein Binding Phospholipid Binding Clathrin Binding Cadherin Binding	Protein Binding
	Biological Process	Endocytosis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Sprouting Angiogenesis
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 30224653) White matter hyperintensities ( 32358547) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)	Asthma ( 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Carotid plaque burden ( 28282560) Chloride levels ( 29403010) Coronary artery disease ( 32469254) Diastolic blood pressure (long-term average) ( 28348047) Estimated glomerular filtration rate ( 31152163 31015462) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Hypertension ( 30487518) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Red blood cell count ( 32888494) Schizophrenia ( 28991256 25056061 29483656 23974872) Sodium levels ( 29403010) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		40 interacting genes: APOE ARRDC1 ARRDC2 ARRDC3 ATXN1 CDIP1 CLTC DAZAP2 EIF3E EPS15 FAIM2 FAM168A FANCM ITSN1 LAPTM5 LITAF MID1 MID2 MLANA PIP4P1 PLEKHB2 PMEPA1 PRKAA2 RNF11 RNF8 SMAD1 SPART TFAP2A THOP1 TRIM23 TRIM26 TRIM62 TUBA1B TXLNA UBA52 UBC WBP1 WBP1L WBP2 YWHAG	6 interacting genes: ABHD16A CNNM2 DPCD EPN2 LIG4 SGTA
Entrez ID		22905	54838
HPRD ID		06271	12567
Ensembl ID		ENSG00000072134	ENSG00000166272
Uniprot IDs		O95208	Q9NX94
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?