ZBTB1 and EWSR1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		ZBTB1	EWSR1
Description		zinc finger and BTB domain containing 1	EWS RNA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Nuclear Body Nuclear Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity K63-linked Polyubiquitin Modification-dependent Protein Binding	Transcription Coregulator Activity RNA Binding Protein Binding Calmodulin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of T Cell Mediated Immunity DNA Repair Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Translesion Synthesis Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation Cellular Response To UV MRNA Transcription By RNA Polymerase II Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Neutrophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31630189)	Breast cancer ( 23535729) Pancreatic cancer ( 25086665) Platelet count ( 27863252) Platelet distribution width ( 32888494)
Interacting Genes		22 interacting genes: AKR7A2 AR EWSR1 FAM161A FANCG HEMGN KAT5 LZTR1 MAML3 MFAP1 NDN PCNA PIH1D2 PIM1 SCNM1 TRAF1 TRIM42 UBC UBE2I ZBTB25 ZNF417 ZNF572	163 interacting genes: ACTL6A AGT ANXA11 ARID1A ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BRME1 BTK C11orf16 CALM1 CCDC7 CCDC91 CD177 CDK12 CEACAM5 CETP CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EPAS1 ERCC5 FAM131C FASN FLI1 FUS FXR2 GNPDA1 GPBP1L1 H2BC15 HBP1 HDAC3 HERPUD1 HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 OGT PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRMT8 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SELENOI SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SMARCC1 SMARCC2 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383
Entrez ID		22890	2130
HPRD ID		15688	00592
Ensembl ID		ENSG00000126804	ENSG00000182944
Uniprot IDs		Q9Y2K1	Q01844
PDB IDs			2CPE
Enriched GO Terms of Interacting Partners?
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