RAB11FIP2 and REPS1

Number of citations of the paper that reports this interaction (PubMedID 12364336)
47

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid, in vitro)

		RAB11FIP2	REPS1
Description		RAB11 family interacting protein 2	RALBP1 associated Eps domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding SH3 Domain Binding
	Biological Process	Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane	Endocytosis Receptor-mediated Endocytosis Endosomal Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834) Type 2 diabetes ( 32499647)
Interacting Genes		22 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PDZD11 PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAE YWHAG	17 interacting genes: ANKRD1 ATF4 CRK FLNC GRB2 HSF1 ITSN2 MZT1 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2 TRAPPC2L WWC2
Entrez ID		22841	85021
HPRD ID		10548	09687
Ensembl ID		ENSG00000107560	ENSG00000135597
Uniprot IDs		Q7L804	B2R7D3 Q96D71
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?
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