TFEC and DCK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TFEC	DCK
Description		transcription factor EC	deoxycytidine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Deoxyadenosine Kinase Activity Deoxycytidine Kinase Activity Deoxyguanosine Kinase Activity ATP Binding Deoxynucleoside Kinase Activity Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II	DAMP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process Phosphorylation
Pathways			Pyrimidine salvage Purine salvage
Drugs			Fludarabine 2'-Deoxycytidine Elacytarabine
Diseases
GWAS		Body mass index ( 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Intraocular pressure ( 29617998 29785010 29235454) Number of sexual partners ( 30643258) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189) Tonsillectomy ( 27182965 28928442)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		11 interacting genes: DCK DEFB127 HNRNPA1 LPAR3 MITF NAPB SMCO4 TET2 TFE3 TFEB ZMAT2	5 interacting genes: DDX19B GOLM1 MED19 RXRG TFEC
Entrez ID		22797	1633
HPRD ID		05294	00507
Ensembl ID		ENSG00000105967	ENSG00000156136
Uniprot IDs		O14948	F5CTF3 P27707
PDB IDs			1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLJ 4JLK 4JLM 4JLN 4KCG 4L5B 4Q18 4Q19 4Q1A 4Q1B 4Q1C 4Q1D 4Q1E 4Q1F 5MQJ 5MQL 5MQT
Enriched GO Terms of Interacting Partners?
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