FHL2 and KPRP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FHL2	KPRP
Description		four and a half LIM domains 2	keratinocyte proline rich protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Focal Adhesion Z Disc M Band	Cytoplasm Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding BHLH Transcription Factor Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Response To Hormone Negative Regulation Of Apoptotic Process Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		PPARA activates gene expression
Drugs
Diseases
GWAS		Bipolar disorder x sex interaction ( 34099189) Body fat mass ( 28552196) Hip circumference adjusted for BMI ( 34021172) Household income (MTAG) ( 31844048) Lung cancer in ever smokers ( 28604730) PR interval ( 32439900) Pulse pressure ( 30224653 30578418) Walking pace ( 33128006)	Asthma ( 31619474) Psoriasis ( 25854761)
Interacting Genes		176 interacting genes: A1CF ABI1 ABLIM1 ADAM17 AK1 AKIP1 AMOT ANKRD55 APP AR ARHGAP9 ATXN1 BANP BARX2 BIN1 BLZF1 BMPR2 BRCA1 C20orf85 C2CD6 CACNA1C CAND2 CAPN1 CARD8 CCDC198 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DAPL1 DCP1A DDIT4L DEAF1 DLGAP1 DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EP300 ESR1 FAM204A FAM214B FHL1 FHL3 FHL5 FOXO1 GAS8 GATAD2B GLYR1 GMEB2 GNG12 GNG4 GOLGA6A GTF2F2 GTF2H1 HAND1 HCK HSF2BP HSPB2 ID3 IDH1 IER3 IFI35 IGFBP5 IKZF1 IKZF4 IL16 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 KIF5B KLF12 KPRP LDLRAP1 LRIF1 MAGEL2 MBD3L1 MCM7 MDM2 MISP MTHFR MYBPC1 MYO15B NBPF6 NIBAN1 NRF1 PFKM PHB2 PHF1 PHF21A PKNOX1 PKNOX2 POGZ POU6F2 PPP1R32 PRDM11 PRDM6 PRR5L PSEN2 PUF60 QRICH1 RAI2 RASL12 REL REV1 RFX3 RIPPLY1 RUNX2 SAP30BP SAXO1 SAXO2 SCNM1 SFPQ SH3RF1 SIGLEC6 SLAIN1 SLC34A1 SMAD2 SMAD3 SMAD4 SNAI1 SOX30 SP2 SPRY4 SREBF2 SRF STAT3 SUMO1P1 TCP10L TNFRSF11A TOX3 TRAF6 TRIM55 TRIM63 TRIM73 TTN TXNRD3 VXN WASHC1 WT1 YPEL3 YY1 ZBTB16 ZBTB25 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF143 ZNF200 ZNF212 ZNF23 ZNF3 ZNF331 ZNF408 ZNF410 ZNF417 ZNF620 ZNF626 ZNF638 ZNF655 ZNF76 ZNF85 ZSCAN9	108 interacting genes: AKAP8L ANKS1A ATG9A BTC C19orf54 CATSPER1 CCDC57 CES1 CKS1B CLCNKA CNFN CNNM3 COL8A1 CREB5 CYSRT1 DARS1-AS1 DMRT3 DYRK1A EIF3E ESR2 FAM221B FAM72B FBXO17 FCHO1 FHL2 FHL3 FRS3 GNE GRAP2 GRB2 GUCD1 HCK HEXIM2 HNRNPF HOXA1 HOXC8 HSD3B7 ITGB4 ITIH6 KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP12-3 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-2 KRTAP4-2 KRTAP4-5 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 LCE3C LCE3D LCE3E LIMS1 LMO2 LNX1 MAPKBP1 MEOX2 MGAT5B MIIP MLH1 NBPF19 NCK2 NID2 NOTCH2NLA NPBWR2 NR4A3 NTN4 NUFIP2 OTX1 PDGFRB PHLDA1 PLA2G10 PLSCR4 POU4F2 PPIL1 PPP1R32 RANBP3 RBP3 RGL2 RNF38 SEMA3B SH3KBP1 SLC15A2 SPRED2 SPRY1 SPRY3 STK16 TEKT4 TFAP2D TNS2 TRIM42 TRIP6 UBASH3A UBASH3B VGLL3 VWC2 ZNF587
Entrez ID		2274	448834
HPRD ID		04026	18838
Ensembl ID		ENSG00000115641	ENSG00000203786
Uniprot IDs		Q14192 Q2XQU9 Q6I9R8	Q5T749
PDB IDs		1X4K 1X4L 2D8Z 2MIU
Enriched GO Terms of Interacting Partners?
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