FGF12 and RBAK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FGF12	RBAK
Description		fibroblast growth factor 12	RB associated KRAB zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Synapse	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Transmembrane Transporter Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Fasting glucose ( 34059833) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels in HIV infection ( 33109212) Height ( 32902719) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Orofacial cleft x maternal periconceptional smoking interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)
Interacting Genes		27 interacting genes: AP2M1 APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 IL2RA LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79	28 interacting genes: AQP1 AR BYSL CARD9 CIB3 CRACR2A EFEMP2 EIF1AD FGF12 GAS8 L3MBTL2 LMO4 LNX1 MAGOHB NEK6 PRKG1 PRPF31 RB1 SCNM1 SLC25A10 TCAF1 TNS2 TRIM41 TSGA10 TXK ZNF121 ZNF330 ZNF648
Entrez ID		2257	57786
HPRD ID		03303	16296
Ensembl ID		ENSG00000114279	ENSG00000146587
Uniprot IDs		P61328	Q9NYW8
PDB IDs		1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?
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