UNC5CL and TOX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UNC5CL	TOX2
Description		unc-5 family C-terminal like	TOX high mobility group box family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Integral Component Of Membrane	Nucleus Nucleoplasm
	Molecular Function	Netrin Receptor Activity Protein Binding Peptidase Activity	Transcription Coactivator Activity Chromatin DNA Binding
	Biological Process	Proteolysis Netrin-activated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 33589840) Esophageal cancer ( 21642993) Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866) Urate levels ( 31578528)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Colorectal cancer ( 30529582) Conduct disorder (symptom count) ( 20585324) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: KRTAP13-2 KRTAP6-1 NFKB1 PGAM1 RELA TOX2 ZMYND12	24 interacting genes: ANKS1A APP CENPP CSTF2T ENKD1 HCK HOMER3 HSF2BP HSFY1 HSFY2 LGALS4 MFHAS1 NDUFAB1 P4HA3 PHF1 RIBC1 SPG21 TCEA2 TEKT4 TEKT5 TLX3 UNC5CL YPEL3 ZNF461
Entrez ID		222643	84969
HPRD ID		09844	12734
Ensembl ID		ENSG00000124602	ENSG00000124191
Uniprot IDs		H8YHX0 Q8IV45	Q96NM4
PDB IDs
Enriched GO Terms of Interacting Partners?
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