ZNF438 and RPP25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF438	RPP25
Description		zinc finger protein 438	ribonuclease P and MRP subunit p25
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Congenital left-sided heart lesions (maternal effect) ( 25138779) Heel bone mineral density ( 30598549) Height ( 25429064 31562340) Multiple sclerosis ( 31604244 21833088) Physiological traits ( 31902109) Pulse pressure ( 27841878) Response to fenofibrate (triglyceride levels) ( 27002377) Rheumatoid arthritis ( 30423114 24390342)	Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Myocardial infarction ( 33532862) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		68 interacting genes: ACOT7 BACH2 BANP BBC3 BYSL CDCA7L CDK18 CEP19 CYSRT1 DMRT3 DPH3 ESRRG FARS2 FRS3 FXR1 GOLGA2 GOLGA6L9 HAPLN2 KCTD7 KRT40 KRTAP10-1 LGALS14 MAGOHB MCC MDFI MID2 MORF4L1 MORN3 MRPL11 MTUS2 MYLIP MYO15B NEK6 NXF1 PIBF1 PICK1 PIH1D2 PLEKHN1 PNMA1 PRMT7 PSMB1 RABEP1 RECK RPP25 SCNM1 SET SMARCD1 SPANXN2 SSX2IP SUV39H1 SYT17 TBC1D22B TP53BP2 TRAF2 TRAPPC2 TRAPPC2B TRIM50 TSGA10 TSTD2 YES1 ZBTB8A ZNF143 ZNF17 ZNF202 ZNF526 ZNF629 ZNF648 ZRANB1	22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438
Entrez ID		220929	54913
HPRD ID		11247	15276
Ensembl ID		ENSG00000183621	ENSG00000178718
Uniprot IDs		Q5T427 Q7Z4V0	Q9BUL9
PDB IDs			6AHR 6AHU 6CWX 6LT7
Enriched GO Terms of Interacting Partners?
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