FAM241B and RNF185

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM241B	RNF185
Description		family with sequence similarity 241 member B	ring finger protein 185
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Ubiquitin-dependent Protein Catabolic Process Autophagy Ubiquitin-dependent ERAD Pathway ERAD Pathway Protein Autoubiquitination Transmembrane Transport ER-associated Misfolded Protein Catabolic Process Positive Regulation Of ERAD Pathway Endoplasmic Reticulum Mannose Trimming
Pathways			ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Type 2 diabetes ( 30054458)	Apolipoprotein A1 levels ( 32203549) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Waist circumference ( 28552196) White blood cell count ( 32888494)
Interacting Genes		27 interacting genes: ADRA1A BIK BLCAP BNIP3 CD79A CGRRF1 CISD2 ERBB2 ERBB3 ERBB4 HSD17B11 KASH5 MOSPD1 MTNR1A REEP4 RNF185 RNF5 SCN3B SLC10A1 SLC39A11 SLC7A1 SUSD6 SYNE4 TMEM234 TMX2 TRHR ZDHHC15	30 interacting genes: APP CGAS CMTM5 CYB561A3 DVL2 FAM241B MALL MS4A13 MTNR1B MYADML2 NIPAL4 TMEM147 TMEM19 TMEM86A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2V1 UBE2W USP21 YIPF2 YIPF4 YIPF6
Entrez ID		219738	91445
HPRD ID		12573	08790
Ensembl ID		ENSG00000171224	ENSG00000138942
Uniprot IDs		A0A024QZL0 Q96D05	A0A024R1F5 A0A024R1H4 Q96GF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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