FAH and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FAH	SERTAD1
Description		fumarylacetoacetate hydrolase	SERTA domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	Fumarylacetoacetase Activity Protein Binding Metal Ion Binding	Protein Binding Transcription Regulator Activity
	Biological Process	Arginine Catabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Homogentisate Catabolic Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription
Pathways		Tyrosine catabolism
Drugs		Fumaric Acid Acetoacetic acid 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		10 interacting genes: ADAMTSL4 CHRDL2 EGFR ETFA KRTAP10-8 KRTAP13-3 KRTAP5-9 PLEKHF2 SERTAD1 TCF4	57 interacting genes: ADCY1 ASB8 ATG12 ATXN7L3 BANF2 C1orf109 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 FXR1 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP NEDD4 P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 TSC1 XIAP ZNF410
Entrez ID		2184	29950
HPRD ID		02040	15326
Ensembl ID		ENSG00000103876	ENSG00000197019
Uniprot IDs		A0A384P5L6 P16930	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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