ACSL4 and DSE

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ACSL4	DSE
Description		acyl-CoA synthetase long chain family member 4	dermatan sulfate epimerase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Membrane Integral Component Of Membrane Neuronal Cell Body Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Cytoplasmic Vesicle Membrane
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Palmitoyl-CoA Ligase Activity	Metal Ion Binding Chondroitin-glucuronate 5-epimerase Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Response To Nutrient Fatty Acid Transport Triglyceride Biosynthetic Process Neuron Differentiation Positive Regulation Of Insulin Secretion Long-chain Fatty-acyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Embryonic Process Involved In Female Pregnancy Dendritic Spine Development Response To Interleukin-15	Heparan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Metabolic Process Dermatan Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Dermatan Sulfate Biosynthetic Process
Pathways		Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs	Dermatan sulfate biosynthesis
Drugs		Icosapent Troglitazone Rosiglitazone
Diseases
GWAS		Mean platelet volume ( 32888494)	Depressive symptoms x dependent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Fast beta electroencephalogram ( 28040410) Height ( 28552196) Heschl's gyrus morphology ( 25130324) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Platelet count ( 32888494) Refractive error ( 32231278) Systemic lupus erythematosus ( 33272962 33536424)
Interacting Genes		4 interacting genes: APP DSE HTATIP2 YWHAQ	2 interacting genes: ACSL4 INTS11
Entrez ID		2182	29940
HPRD ID		02152	05807
Ensembl ID		ENSG00000068366	ENSG00000111817
Uniprot IDs		O60488 Q8TAF6	A0A2R8YE23 A0A2U3TZJ0 B7Z1T3 B7Z765 Q9UL01
PDB IDs			6HZN
Enriched GO Terms of Interacting Partners?
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