Description |
F2R like trypsin receptor 1 |
coagulation factor II, thrombin |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Lepirudin
- Bivalirudin
- Drotrecogin alfa
- Coagulation Factor IX (Recombinant)
- Menadione
- Argatroban
- Proflavine
- Zinc
- 2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide
- Beta-(2-Naphthyl)-Alanine
- Hemi-Babim
- 2-(2-hydroxy-phenyl)-3H-benzoimidazole-5-carboxamidine
- 4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide
- 4-Iodobenzo[B]Thiophene-2-Carboxamidine
- CRA_8696
- gamma-carboxy-L-glutamic acid
- 6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
- Lysophosphotidylserine
- N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE
- TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE
- 2-[3-chloro-6-[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]imino-1-hydroxypyridin-2-yl]-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide
- 1-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANE
- 1-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANE
- Suramin
- Ximelagatran
- Flovagatran
- Thrombomodulin Alfa
- Human C1-esterase inhibitor
- Dabigatran etexilate
- methyl L-phenylalaninate
- [(2R)-1-[(2S)-2-[[(2S,3S)-1-Chloro-6-(diaminomethylideneamino)-2-hydroxyhexan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]azanium
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide
- N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE
- 6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE
- 6-CARBAMIMIDOYL-2-[2-HYDROXY-6-(4-HYDROXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID
- 6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID
- N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide
- 1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE
- 1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide
- D-leucyl-N-(3-chlorobenzyl)-L-prolinamide
- D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide
- 1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide
- N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
- 1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide
- D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide
- (3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline
- D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide
- beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide
- 2-[2-(4-Chloro-Phenylsulfanyl)-Acetylamino]-3-(4-Guanidino-Phenyl)-Propionamide
- 3-Carbamimidamido-1,1-diphenylurea
- N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINE
- (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide
- D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide
- D-phenylalanyl-N-benzyl-L-prolinamide
- N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE
- 3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide
- (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE
- 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE
- GW-813893
- N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE
- 4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL
- 2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
- 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)
- 1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE
- 4-TERT-BUTYLBENZENESULFONIC ACID
- 3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
- 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
- 1-(2-{[(6-amino-2-methylpyridin-3-yl)methyl]amino}ethyl)-6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-1,4-dihydropyrazin-2-ol
- (3Z,6S)-6-Chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-2-piperidinyl]ethyl}imino)-2-piperazinol
- N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE
- N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE
- 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE
- 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDE
- 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE
- 3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER
- AC-(D)Phe-pro-borolys-OH
- AC-(D)PHE-PRO-BOROHOMOLYS-OH
- AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH
- N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide
- 4-Hydroxyphenylpyruvic acid
- 4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE
- (3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE
- 4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE
- 1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE
- [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE
- N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE
- N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide
- 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE
- 3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE
- {(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate
- N-Methylphenylalanyl-N-[(trans-4-aminocyclohexyl)methyl]-L-prolinamide
- 2-Naphthalenesulfonic acid
- [PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE
- 4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE
- 1-[(4S)-4-amino-5-(1,3-benzothiazol-2-yl)-5-oxopentyl]guanidine
- Turoctocog alfa
- Copper
- Conestat alfa
- Kappadione
- Antithrombin Alfa
- Nafamostat
- Gabexate
- Anti-inhibitor coagulant complex
- Coagulation Factor IX Human
- Zinc acetate
- Turoctocog alfa pegol
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Diseases |
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GWAS |
- Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171)
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Interacting Genes |
84 interacting genes:
ABCC8
ABHD14A
ADCY2
ANKRA2
ARL6IP1
ATP2A2
ATP2B1
ATP2C1
BSG
CANX
CAPN1
CAPN2
CAPNS1
CBL
CD63
CD81
CLPTM1
CNN3
COPS5
CRLS1
CTNNA1
CTSG
CYFIP2
DNMT3L
ELANE
ERGIC3
F2
F2R
GJB6
GJC2
GPRASP1
HERPUD1
HLA-E
HMOX2
HSPA1B
ICAM2
JMY
KDELR1
KLC1
LMNA
MAP1B
MFSD10
MORN4
NAT14
NBPF15
NUMA1
OSTC
P4HTM
PCBD2
PHLDA1
PIGU
PLG
PPM1J
PRNP
PRRT2
PRTN3
PSMC3
PTDSS2
QSER1
R3HDM1
RAD17
RGR
RTN1
RTN4
SCN1B
SDHD
SLC12A5
SLC18B1
SLC1A4
SLC31A2
SLC32A1
SLC35A1
SLC39A13
SLC43A2
ST14
SYNGR2
TMBIM1
TMED1
TMEM161A
TMEM62
TMX2
WFS1
YIPF1
YIPF6
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42 interacting genes:
AANAT
AKR7A2
AMBP
C6
CPB2
DDIT3
F11
F13A1
F2R
F2RL1
F2RL2
F2RL3
F5
F8
F9
FGA
GGCX
GP1BA
GP5
HGFAC
IGFBP3
IGFBP5
ITGA2B
KNG1
MAPT
PLAU
PROC
PROS1
PROZ
SERPINA5
SERPINB6
SERPINB8
SERPINC1
SERPIND1
SERPINE1
SERPINE2
SERPING1
SPP1
ST13
THBD
THBS1
TRAF6
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Entrez ID |
2150 |
2147 |
HPRD ID |
02960 |
01488 |
Ensembl ID |
ENSG00000164251
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ENSG00000180210
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Uniprot IDs |
P55085
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P00734
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PDB IDs |
5NDD
5NDZ
5NJ6
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1A2C
1A3B
1A3E
1A46
1A4W
1A5G
1A61
1ABI
1ABJ
1AD8
1AE8
1AFE
1AHT
1AI8
1AIX
1AWF
1AWH
1AY6
1B5G
1B7X
1BA8
1BB0
1BCU
1BHX
1BMM
1BMN
1BTH
1C1U
1C1V
1C1W
1C4U
1C4V
1C4Y
1C5L
1C5N
1C5O
1CA8
1D3D
1D3P
1D3Q
1D3T
1D4P
1D6W
1D9I
1DE7
1DIT
1DM4
1DOJ
1DWB
1DWC
1DWD
1DWE
1DX5
1E0F
1EB1
1EOJ
1EOL
1FPC
1FPH
1G30
1G32
1G37
1GHV
1GHW
1GHX
1GHY
1GJ4
1GJ5
1H8D
1H8I
1HAG
1HAH
1HAI
1HAO
1HAP
1HBT
1HDT
1HGT
1HLT
1HUT
1HXE
1HXF
1IHS
1IHT
1JMO
1JOU
1JWT
1K21
1K22
1KTS
1KTT
1LHC
1LHD
1LHE
1LHF
1LHG
1MH0
1MU6
1MU8
1MUE
1NM6
1NO9
1NRN
1NRO
1NRP
1NRQ
1NRR
1NRS
1NT1
1NU7
1NU9
1NY2
1NZQ
1O0D
1O2G
1O5G
1OOK
1OYT
1P8V
1PPB
1QBV
1QHR
1QJ1
1QJ6
1QJ7
1QUR
1RD3
1RIW
1SB1
1SFQ
1SG8
1SGI
1SHH
1SL3
1SR5
1T4U
1T4V
1TA2
1TA6
1TB6
1TBZ
1THP
1THR
1THS
1TMB
1TMT
1TMU
1TOM
1TQ0
1TQ7
1TWX
1UMA
1UVS
1VR1
1VZQ
1W7G
1WAY
1WBG
1XM1
1XMN
1YPE
1YPG
1YPJ
1YPK
1YPL
1YPM
1Z71
1Z8I
1Z8J
1ZGI
1ZGV
1ZRB
2A0Q
2A2X
2A45
2AFQ
2ANK
2ANM
2B5T
2BDY
2BVR
2BVS
2BVX
2BXT
2BXU
2C8W
2C8X
2C8Y
2C8Z
2C90
2C93
2CF8
2CF9
2CN0
2FEQ
2FES
2GDE
2GP9
2H9T
2HGT
2HNT
2HPP
2HPQ
2HWL
2JH0
2JH5
2JH6
2OD3
2PGB
2PGQ
2PKS
2PW8
2R2M
2THF
2UUF
2UUJ
2UUK
2V3H
2V3O
2ZC9
2ZDA
2ZDV
2ZF0
2ZFF
2ZFP
2ZFQ
2ZFR
2ZG0
2ZGB
2ZGX
2ZHE
2ZHF
2ZHQ
2ZHW
2ZI2
2ZIQ
2ZNK
2ZO3
3B23
3B9F
3BEF
3BEI
3BF6
3BIU
3BIV
3BV9
3C1K
3C27
3D49
3DA9
3DD2
3DHK
3DT0
3DUX
3E6P
3EE0
3EGK
3EQ0
3F68
3GIC
3GIS
3HAT
3HKJ
3HTC
3JZ1
3JZ2
3K65
3LDX
3LU9
3NXP
3P17
3P6Z
3P70
3PMH
3PO1
3QDZ
3QGN
3QLP
3QTO
3QTV
3QWC
3QX5
3R3G
3RLW
3RLY
3RM0
3RM2
3RML
3RMM
3RMN
3RMO
3S7H
3S7K
3SHA
3SHC
3SI3
3SI4
3SQE
3SQH
3SV2
3T5F
3TU7
3U69
3U8O
3U8R
3U8T
3U98
3U9A
3UTU
3UWJ
3VXE
3VXF
4AX9
4AYV
4AYY
4AZ2
4BAH
4BAK
4BAM
4BAN
4BAO
4BAQ
4BOH
4CH2
4CH8
4DIH
4DII
4DT7
4DY7
4E05
4E06
4E7R
4H6S
4H6T
4HFP
4HTC
4HZH
4I7Y
4LOY
4LXB
4LZ1
4LZ4
4MLF
4NZQ
4O03
4RKJ
4RKO
4RN6
4THN
4UD9
4UDW
4UE7
4UEH
4UFD
4UFE
4UFF
4UFG
4YES
5A2M
5AF9
5AFY
5AFZ
5AHG
5CMX
5DO4
5E8E
5EDK
5EDM
5EW1
5EW2
5GDS
5GIM
5JDU
5JFD
5JZY
5L6N
5MJT
5MLS
5MM6
5NHU
5TO3
5Z5W
5Z5X
6BJR
6C2W
6EO6
6EO7
6EO8
6EO9
6V5T
7KME
8KME
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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