DMTN and PTOV1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DMTN	PTOV1
Description		dematin actin binding protein	PTOV1 extended AT-hook containing adaptor protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Filament Plasma Membrane Endomembrane System Postsynaptic Density Spectrin-associated Cytoskeleton Actin Cytoskeleton Cortical Cytoskeleton Platelet Dense Tubular Network Membrane Cell Projection Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Regulator Complex Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Signaling Receptor Binding Protein Binding Spectrin Binding Protein Self-association Actin Filament Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Regulation Of Lamellipodium Assembly Positive Regulation Of Fibroblast Migration Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Cell-substrate Adhesion Lamellipodium Assembly Actin Cytoskeleton Organization Positive Regulation Of Blood Coagulation Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Peptidyl-serine Phosphorylation Calcium-mediated Signaling Using Intracellular Calcium Source Calcium-mediated Signaling Using Extracellular Calcium Source Erythrocyte Development Negative Regulation Of Peptidyl-tyrosine Phosphorylation Actin Filament Bundle Assembly Regulation Of Filopodium Assembly Actin Filament Capping Negative Regulation Of Focal Adhesion Assembly Protein-containing Complex Assembly Protein Secretion By Platelet Cellular Response To Calcium Ion Cellular Response To CAMP Positive Regulation Of Wound Healing Negative Regulation Of Protein Targeting To Membrane Actin Filament Reorganization Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Platelet Aggregation Positive Regulation Of Integrin-mediated Signaling Pathway	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Apolipoprotein B levels ( 32203549) Gamma glutamyl transferase levels ( 33339817) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 30275531)
Interacting Genes		16 interacting genes: ACTB ACTC1 APP CEP76 DYNC1LI2 EPB42 GOLGA2 NEDD4L PRKACA PROCR PTOV1 SNCA SNRPD2 SPTB TEX11 TRAF2	9 interacting genes: CCR4 DMTN HDAC6 PIN1 RACK1 SPTAN1 TMCC2 UBC USP16
Entrez ID		2039	53635
HPRD ID		00506	17929
Ensembl ID		ENSG00000158856	ENSG00000104960
Uniprot IDs		Q08495	A0A0C4DGR2 Q86YD1
PDB IDs		1QZP 1ZV6
Enriched GO Terms of Interacting Partners?
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