ENO1 and RXFP3

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		ENO1	RXFP3
Description		enolase 1	relaxin family peptide receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cell Surface Membrane M Band Extracellular Exosome Cell Cortex Region	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Magnesium Ion Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Phosphopyruvate Hydratase Activity Protein Binding Protein Homodimerization Activity Cadherin Binding GTPase Binding	G Protein-coupled Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Glycolytic Process Response To Virus Positive Regulation Of Plasminogen Activation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Muscle Contraction Canonical Glycolysis Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Biosynthetic Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Cytokinesis
Pathways		Glycolysis Gluconeogenesis Manipulation of host energy metabolism	G alpha (i) signalling events Relaxin receptors
Drugs		Zinc Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Asthma ( 30929738) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood protein levels ( 30072576) Feeling tense ( 29500382) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Tonsillectomy ( 27182965 28928442) White blood cell count ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		65 interacting genes: AGTPBP1 ALDOA AMBP ANK3 ARID1B BCL6 BHLHE40 BRCA1 CBX5 CHEK2 CLK1 COL14A1 CYSLTR2 DES DUX4 FANCA FHL1 FLNC FXR1 FYN GLIS3 GRB2 HDAC1 HEMGN HEY2 HK2 HSP90AB1 HSPA8 HSPB2 ITGB1 IVNS1ABP KDM2A LIG4 LINC01554 LONRF3 MCPH1 MED13 MYOC NCOR1 OGT P4HB PAF1 PCNA PLG PPP2R5E RXFP3 SERPING1 SET SGCG SNAPC3 SRC SUMO2 SUMO4 TCAP TEAD1 TERT TNFRSF14 TRAPPC2 TTN TUBA1A UBE3A UPF2 YWHAQ YWHAZ ZBTB44	10 interacting genes: APP ENO1 GNAS HSP90B1 KATNB1 NCKIPSD RLN3 TMEM248 TTC19 YWHAE
Entrez ID		2023	51289
HPRD ID		01400	17979
Ensembl ID		ENSG00000074800	ENSG00000182631
Uniprot IDs		A0A024R4F1 P06733	Q9NSD7
PDB IDs		2PSN 3B97 5JLZ 5LAX 5NI9 5NIG 5OCK
Enriched GO Terms of Interacting Partners?
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