PDE12 and DNAH12

		PDE12	DNAH12
Description		phosphodiesterase 12	dynein axonemal heavy chain 12
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Cytoplasm Microtubule Cilium Dynein Complex
	Molecular Function	3'-5'-exoribonuclease Activity Exonuclease Activity Poly(A)-specific Ribonuclease Activity Oligoribonucleotidase Activity Metal Ion Binding	ATP Binding Minus-end-directed Microtubule Motor Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Mitochondrial MRNA Catabolic Process MRNA Processing Cellular Response To Interferon-alpha Regulation Of Mitochondrial MRNA Stability Positive Regulation Of Viral Genome Replication Defense Response To Virus Negative Regulation Of Cell Death Cellular Response To Interferon-gamma Cellular Response To DsRNA Nucleic Acid Phosphodiester Bond Hydrolysis Negative Regulation Of Oxidative Phosphorylation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Microtubule-based Movement
Pathways		OAS antiviral response
Drugs
Diseases
GWAS			Lung function (FEV1) ( 30061609) Monocyte percentage of white cells ( 32888494) Working memory ( 31598132)
Interacting Genes		3 interacting genes: DNAH12 FBXO7 UBC	1 interacting genes: PDE12
Entrez ID		201626	201625
HPRD ID		11842	08281
Ensembl ID		ENSG00000174840	ENSG00000174844
Uniprot IDs		F6T1Q0 Q6L8Q7	Q6ZR08
PDB IDs		4Z0V 4Z2B 4ZKF
Enriched GO Terms of Interacting Partners?
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