ARL13B and ICMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARL13B	ICMT
Description		ADP ribosylation factor like GTPase 13B	isoprenylcysteine carboxyl methyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cilium Axoneme Motile Cilium Ciliary Membrane Non-motile Cilium	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein C-terminal Carboxyl O-methyltransferase Activity Protein C-terminal S-isoprenylcysteine Carboxyl O-methyltransferase Activity Protein Binding
	Biological Process	Heart Looping Smoothened Signaling Pathway Dorsal/ventral Pattern Formation Response To Lithium Ion Neural Tube Patterning Interneuron Migration From The Subpallium To The Cortex Formation Of Radial Glial Scaffolds Cilium Assembly Left/right Axis Specification Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly	Cellular Protein Modification Process C-terminal Protein Methylation Protein Targeting To Membrane
Pathways		ARL13B-mediated ciliary trafficking of INPP5E RHOQ GTPase cycle RHOJ GTPase cycle Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Gamma carboxylation, hypusine formation and arylsulfatase activation RAS processing
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Resting heart rate ( 27798624 28270201)
Interacting Genes		134 interacting genes: ACSF2 AIG1 ALG3 ANKRD46 AOC3 AQP10 ARL6 B4GALNT2 BMP10 BNIP3 BRICD5 C1GALT1 C2CD2L C4orf3 CCDC167 CCL4 CCL4L2 CD151 CD302 CD53 CDIPT CFHR5 CLDN4 CLDN8 CLEC4G CLEC7A CLN6 CMTM3 CMTM7 COL8A2 CRYBG3 CSGALNACT2 CTSA CXCL16 CYB561D2 DHFR2 EBP EMP1 ENTPD3 FAXDC2 FDFT1 FKBP8 FUNDC2 FXYD6 GAD2 GIMAP1 GIMAP5 GJB2 GOSR2 GPR37L1 HMOX1 HMOX2 HOMER3 ICMT ITGAM JAGN1 KCNJ2 KLRG1 LEPROTL1 LPAR3 MAL2 MALL MMD MOSPD3 MUCL1 MYADML2 NAT8 NINJ2 NKG7 NRM NUCB2 ORMDL1 ORMDL3 PAEP PDZK1IP1 PGAP2 PLN PLP1 PLPP4 PLPPR2 PMP22 PRB1 PTPN9 RIOX2 RTP2 S100A2 SACM1L SEMA4G SLC13A3 SLC2A5 SLC35A1 SLC35B1 SLC38A7 SLC39A2 SMAGP SPN STRIT1 STX1A STX7 TECR TEX264 TFRC THSD7A THSD7B TM6SF2 TMEM11 TMEM121 TMEM128 TMEM14C TMEM187 TMEM190 TMEM218 TMEM229B TMEM254 TMEM43 TMEM54 TMEM65 TMEM79 TMEM86B TMEM97 TMUB2 TNFRSF10C TNMD TRARG1 TSPO2 UBE2I VAMP1 VAMP2 VAMP3 VAMP4 VSTM1 WFDC2 YIPF6 ZDHHC15	12 interacting genes: AQP6 ARL13B HRAS JAGN1 KCNJ6 MUC1 PDZK1IP1 RAC1 RAC2 RHOA RNF19B TRIM32
Entrez ID		200894	23463
HPRD ID		12334	09321
Ensembl ID		ENSG00000169379	ENSG00000116237
Uniprot IDs		Q3SXY8	A0A024R4F6 B3KS61 O60725
PDB IDs
Enriched GO Terms of Interacting Partners?
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