ELN and FBLN2

Number of citations of the paper that reports this interaction (PubMedID 10544250)
19

Data Source:
HPRD (in vitro)

		ELN	FBLN2
Description		elastin	fibulin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Elastic Fiber	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Outflow Tract Morphogenesis Aortic Valve Morphogenesis Skeletal Muscle Tissue Development Respiratory Gaseous Exchange By Respiratory System Blood Circulation Animal Organ Morphogenesis Extracellular Matrix Organization Regulation Of Actin Filament Polymerization Stress Fiber Assembly Regulation Of Smooth Muscle Cell Proliferation	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		Rofecoxib
Diseases
GWAS		Diverticular disease ( 30177863) Height ( 31562340)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		23 interacting genes: ALMS1 ASS1 BGN CKMT2 CLU DCN ELANE FBLN1 FBLN2 FBN1 FBN2 FCN1 FKBP10 LGALS3 LOX LOXL1 LYZ MAGEH1 MFAP2 MTDH NID2 PRTN3 SPINK1	33 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HOXA1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D MRPS25 NID1 NUFIP2 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		2006	2199
HPRD ID		00556	00630
Ensembl ID		ENSG00000049540	ENSG00000163520
Uniprot IDs		B3KRT8 B4E3S4 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 Q59H17 Q6ZUN2 Q8NBI4	P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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