EHHADH and KCTD6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EHHADH	KCTD6
Description		enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	potassium channel tetramerization domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Cytosol M Band
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Enzyme Binding NAD+ Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Growth Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs		NADH
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)	Hepcidin/transferrin saturation ratio ( 27846281) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		100 interacting genes: AARS2 ACTB ACTG1 ADARB1 ANKRD36B ARMC12 ARMCX3 BHLHE40 BOLL CAT CBS CCDC102B CCDC13 CDR2L CEP83 CISD2 CLDN18 CLDN5 CLK2 CMTM6 COQ9 CYB561 CYB561A3 DAAM2 DERL3 DES EMP1 ERGIC1 FGF14 FUNDC1 GAS8 GMCL1 GRIPAP1 HID1 HIP1 HSD17B11 HTATIP2 JAGN1 KCTD6 KCTD9 KRTAP10-7 KRTAP4-11 LCN2 LEPROTL1 LYPD5 LZTFL1 LZTS2 MAB21L3 MID1 MTUS2 NACC1 NECAB2 OPRM1 ORMDL1 PAQR8 PICK1 PNMA1 PNMA5 PPP1R12C PRKRA PSTPIP1 PTGES REL RNF4 RPRM RUSF1 SCARA5 SCP2 SDR16C5 SGCB SLC14A2 SLC39A2 SMIM5 SMN1 SMN2 SSNA1 SSX2IP SYNGR3 TMEM121 TMEM17 TMEM31 TMEM35A TNIP1 TPP2 TRAF1 TRIM21 TRIM23 TRIM27 TRIM41 TRIM5 TRIM54 TRIM55 TRIM63 VAC14 ZBTB10 ZBTB26 ZBTB8A ZBTB9 ZCCHC17 ZRANB1	28 interacting genes: ACTN1 ACTN3 ANK1 BAG4 C8orf33 CDC23 CTNND1 CUL3 EHHADH ERBB2 FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 MOS NTAQ1 PICK1 PPIG PRPF31 PSMA1 REL SDCBP TBC1D2 TCEANC TEPSIN ZCCHC10
Entrez ID		1962	200845
HPRD ID		06125	13769
Ensembl ID		ENSG00000113790	ENSG00000168301
Uniprot IDs		Q08426	Q8NC69
PDB IDs
Enriched GO Terms of Interacting Partners?
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